Supt6 - SPT6, histone chaperone and transcription elongation factor

Predicted to enable histone binding activity and nucleosome binding activity. Involved in several processes, including negative regulation of histone H3-K27 methylation; regulation of mRNA export from nucleus; and regulation of nucleobase-containing compound metabolic process. Acts upstream of or within blastocyst formation. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Predicted to be active in transcriptionally active chromatin. Is expressed in several structures, including brain; early conceptus; genitourinary system; liver; and spleen. Orthologous to human SUPT6H (SPT6 homolog, histone chaperone and transcription elongation factor). [provided by Alliance of Genome Resources, Apr 2022]