Gan - giant axonal neuropathy

Predicted to be involved in protein ubiquitination. Predicted to act upstream of or within cytoskeleton organization. Predicted to be located in cytoplasm. Predicted to be part of Cul3-RING ubiquitin ligase complex. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and respiratory system. Used to study giant axonal neuropathy 1. Human ortholog(s) of this gene implicated in giant axonal neuropathy 1. Orthologous to human GAN (gigaxonin). [provided by Alliance of Genome Resources, Apr 2022]