Creb3l3 - cAMP responsive element binding protein 3-like 3

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein dimerization activity. Involved in positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress. Located in membrane and nucleus. Is expressed in brain; duodenum epithelium; genitourinary system; and liver. Orthologous to human CREB3L3 (cAMP responsive element binding protein 3 like 3). [provided by Alliance of Genome Resources, Apr 2022]