Enables identical protein binding activity. Acts upstream of or within myotube differentiation and store-operated calcium entry. Located in endoplasmic reticulum. Part of protein-containing complex. Is expressed in several structures, including alimentary system; central nervous system; gonad; hemolymphoid system gland; and musculature. Human ortholog(s) of this gene implicated in Stormorken syndrome; immunodeficiency 10; and tubular aggregate myopathy 1. Orthologous to human STIM1 (stromal interaction molecule 1). [provided by Alliance of Genome Resources, Apr 2022]