Setd1b - SET domain containing 1B

Predicted to enable RNA binding activity and histone-lysine N-methyltransferase activity. Predicted to contribute to histone methyltransferase activity (H3-K4 specific). Predicted to be involved in histone H3-K4 dimethylation; histone H3-K4 monomethylation; and histone H3-K4 trimethylation. Predicted to act upstream of or within chromatin organization and methylation. Located in nucleus. Is expressed in several structures, including brain; cranium; early conceptus; oocyte; and sensory organ. Orthologous to human SETD1B (SET domain containing 1B, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]