Rnf43 - ring finger protein 43

Predicted to enable frizzled binding activity and ubiquitin protein ligase activity. Involved in negative regulation of Wnt signaling pathway and stem cell proliferation. Predicted to be located in endoplasmic reticulum; nucleus; and plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in alimentary system; genitourinary system; and lung. Orthologous to human RNF43 (ring finger protein 43). [provided by Alliance of Genome Resources, Apr 2022]