Sptbn1 - spectrin beta, non-erythrocytic 1

Predicted to enable GTPase binding activity; actin filament binding activity; and ankyrin binding activity. Predicted to be a structural constituent of cytoskeleton. Involved in protein localization to plasma membrane. Acts upstream of or within common-partner SMAD protein phosphorylation and regulation of SMAD protein signal transduction. Located in several cellular components, including M band; axolemma; and cuticular plate. Is expressed in several structures, including brain; liver; sciatic nerve; spinal cord; and spleen. Used to study Beckwith-Wiedemann syndrome. Orthologous to human SPTBN1 (spectrin beta, non-erythrocytic 1). [provided by Alliance of Genome Resources, Apr 2022]