Serpini1 - serine (or cysteine) peptidase inhibitor, clade I, member 1

Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of endopeptidase activity; positive regulation of neuron projection development; and regulation of cell adhesion. Predicted to act upstream of or within negative regulation of peptidase activity. Located in neuronal cell body and secretory granule lumen. Is expressed in several structures, including early conceptus; enteric nervous system; intestine; retina; and secondary oocyte. Used to study familial encephalopathy with neuroserpin inclusion bodies. Human ortholog(s) of this gene implicated in familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINI1 (serpin family I member 1). [provided by Alliance of Genome Resources, Apr 2022]