Slc6a2 - solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

Enables monoamine transmembrane transporter activity and neurotransmitter transmembrane transporter activity. Involved in neurotransmitter reuptake and norepinephrine uptake. Acts upstream of or within neurotransmitter transport and response to pain. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in neuron projection; neuronal cell body membrane; and presynaptic membrane. Predicted to be integral component of plasma membrane. Is expressed in adrenal gland; lip; nervous system; sensory organ; and testis. Used to study heart conduction disease. Human ortholog(s) of this gene implicated in hypertension and neurocirculatory asthenia. Orthologous to human SLC6A2 (solute carrier family 6 member 2). [provided by Alliance of Genome Resources, Apr 2022]