Slc2a4 - solute carrier family 2 (facilitated glucose transporter), member 4
Alias:
GT2
twgy
Glut4
Glut-4
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables glucose transmembrane transporter activity. Involved in cellular response to insulin stimulus. Acts upstream of or within several processes, including amylopectin biosynthetic process; brown fat cell differentiation; and glucose import in response to insulin stimulus. Located in several cellular components, including cytoplasmic vesicle; extracellular exosome; and sarcolemma. Is integral component of plasma membrane. Is expressed in several structures, including adipose tissue; adrenal gland; alimentary system; brain; and genitourinary system. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in type 2 diabetes mellitus. Orthologous to human SLC2A4 (solute carrier family 2 member 4). [provided by Alliance of Genome Resources, Apr 2022]