Clpb - ClpB caseinolytic peptidase B

Predicted to enable ATP hydrolysis activity. Predicted to be involved in RIG-I signaling pathway; antiviral innate immune response; and cellular response to heat. Located in mitochondrion. Is expressed in several structures, including central nervous system; inner cell mass; limb; paravertebral ganglion; and retina. Human ortholog(s) of this gene implicated in 3-methylglutaconic aciduria with cataracts, neurologic involvement and neutropenia. Orthologous to human CLPB (caseinolytic mitochondrial matrix peptidase chaperone subunit B). [provided by Alliance of Genome Resources, Apr 2022]