Sim1 - single-minded family bHLH transcription factor 1
Alias:
mSIM1
bHLHe14
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables protein heterodimerization activity. Acts upstream of or within regulation of transcription, DNA-templated and ureteric bud development. Located in nucleus. Is expressed in several structures, including central nervous system; limb bud; metanephros; paraxial mesenchyme; and sensory organ. Used to study obesity. Human ortholog(s) of this gene implicated in obesity. Orthologous to human SIM1 (SIM bHLH transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]