St3gal3 - ST3 beta-galactoside alpha-2,3-sialyltransferase 3

Enables beta-galactoside (CMP) alpha-2,3-sialyltransferase activity. Involved in ganglioside biosynthetic process via lactosylceramide. Acts upstream of or within protein glycosylation. Predicted to be located in Golgi apparatus and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; central nervous system; cranium; eye; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in autosomal recessive non-syndromic intellectual disability and developmental and epileptic encephalopathy 15. Orthologous to human ST3GAL3 (ST3 beta-galactoside alpha-2,3-sialyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]