Cyfip1 - cytoplasmic FMR1 interacting protein 1

Enables translation regulator activity. Involved in several processes, including dendrite extension; positive regulation of neurotrophin TRK receptor signaling pathway; and regulation of modification of postsynaptic actin cytoskeleton. Acts upstream of or within lamellipodium assembly. Located in several cellular components, including lamellipodium; perinuclear region of cytoplasm; and postsynapse. Part of mRNA cap binding activity complex. Is expressed in several structures, including embryo mesenchyme; lung; nervous system; skeletal muscle; and tooth. Human ortholog(s) of this gene implicated in autism spectrum disorder and schizophrenia. Orthologous to human CYFIP1 (cytoplasmic FMR1 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]