Shc1 - src homology 2 domain-containing transforming protein C1

Enables epidermal growth factor binding activity; identical protein binding activity; and signaling receptor binding activity. Acts upstream of or within several processes, including actin cytoskeleton reorganization; circulatory system development; and positive regulation of MAPK cascade. Predicted to be located in endosome membrane and nucleus. Predicted to be part of Shc-EGFR complex. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; heart; liver; skeleton; and skin. Orthologous to human SHC1 (SHC adaptor protein 1). [provided by Alliance of Genome Resources, Apr 2022]