Sema6b - sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B

Enables semaphorin receptor binding activity. Involved in axon guidance and hippocampus development. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be active in extracellular space. Predicted to be integral component of plasma membrane. Is expressed in several structures, including genitourinary system; liver; musculature; spinal cord; and spleen. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy. Orthologous to human SEMA6B (semaphorin 6B). [provided by Alliance of Genome Resources, Apr 2022]