Sema4d - sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

Enables semaphorin receptor binding activity. Involved in several processes, including negative regulation of osteoblast differentiation; positive regulation of inhibitory synapse assembly; and regulation of phosphate metabolic process. Acts upstream of or within positive regulation of axonogenesis. Located in extracellular space. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and respiratory system. Orthologous to human SEMA4D (semaphorin 4D). [provided by Alliance of Genome Resources, Apr 2022]