Sema3e - sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E

Enables semaphorin receptor binding activity. Involved in several processes, including angiogenesis; negative regulation of angiogenesis; and regulation of actin cytoskeleton reorganization. Located in extracellular space. Is expressed in several structures, including hemolymphoid system gland; nervous system; nose; palatal shelf mesenchyme; and trunk mesenchyme. Human ortholog(s) of this gene implicated in CHARGE syndrome. Orthologous to human SEMA3E (semaphorin 3E). [provided by Alliance of Genome Resources, Apr 2022]