Scn3a - sodium channel, voltage-gated, type III, alpha

Predicted to enable calmodulin binding activity; sodium ion binding activity; and voltage-gated sodium channel activity. Predicted to be involved in several processes, including neuronal action potential; response to pyrethroid; and sodium ion transmembrane transport. Predicted to act upstream of or within regulation of ion transmembrane transport and sodium ion transport. Located in cytoplasm and membrane. Is expressed in cerebral cortex; heart; sciatic nerve; sympathetic ganglion; and telencephalon. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 62 and focal epilepsy. Orthologous to human SCN3A (sodium voltage-gated channel alpha subunit 3). [provided by Alliance of Genome Resources, Apr 2022]