Sars1 - seryl-aminoacyl-tRNA synthetase

Predicted to enable several functions, including nucleic acid binding activity; protein homodimerization activity; and serine-tRNA ligase activity. Predicted to be involved in negative regulation of angiogenesis; negative regulation of macromolecule metabolic process; and seryl-tRNA aminoacylation. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; egg cylinder; and genitourinary system. Human ortholog(s) of this gene implicated in intellectual disability. Orthologous to human SARS1 (seryl-tRNA synthetase 1). [provided by Alliance of Genome Resources, Apr 2022]