Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin protein ligase activity. Involved in several processes, including negative regulation of NLRP3 inflammasome complex assembly; negative regulation of cytokine production; and protein autoubiquitination. Acts upstream of or within response to bacterium. Located in cytoplasm. Is expressed in genitourinary system and limb. Orthologous to human TRIM5 (tripartite motif containing 5). [provided by Alliance of Genome Resources, Apr 2022]