Sub1 - SUB1 homolog, transcriptional regulator

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within SMAD protein signal transduction. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including branchial arch; central nervous system; genitourinary system; limb; and sensory organ. Orthologous to human SUB1 (SUB1 regulator of transcription). [provided by Alliance of Genome Resources, Apr 2022]