Polr1c - polymerase (RNA) I polypeptide C

Predicted to enable DNA binding activity and protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Predicted to be involved in transcription, DNA-templated. Part of RNA polymerase I complex. Is expressed in several structures, including alimentary system; genitourinary system; midbrain; respiratory system; and telencephalon. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Orthologous to human POLR1C (RNA polymerase I and III subunit C). [provided by Alliance of Genome Resources, Apr 2022]