Rock2 - Rho-associated coiled-coil containing protein kinase 2
Alias:
Rock2m
Rock-II
ROKalpha
mKIAA0619
Rho-kinase
B230113H15Rik
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
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Enables protein serine/threonine kinase activity. Involved in several processes, including positive regulation of macromolecule metabolic process; protein phosphorylation; and regulation of signal transduction. Acts upstream of or within several processes, including extrinsic apoptotic signaling pathway via death domain receptors; nervous system development; and positive regulation of centrosome duplication. Located in Schaffer collateral - CA1 synapse; glutamatergic synapse; and spindle pole centrosome. Is expressed in several structures, including central nervous system; genitourinary system; heart; musculature; and somite. Orthologous to human ROCK2 (Rho associated coiled-coil containing protein kinase 2). [provided by Alliance of Genome Resources, Apr 2022]