Trim27 - tripartite motif-containing 27

Predicted to enable several functions, including protein homodimerization activity; transcription coactivator activity; and ubiquitin-like protein transferase activity. Involved in innate immune response; negative regulation of viral transcription; and suppression of viral release by host. Acts upstream of or within negative regulation of transcription by RNA polymerase II and positive regulation of actin nucleation. Located in cytoplasm. Is expressed in several structures, including central nervous system; genitourinary system; liver; lung; and retina. Orthologous to human TRIM27 (tripartite motif containing 27). [provided by Alliance of Genome Resources, Apr 2022]