Reln - reelin

Enables very-low-density lipoprotein particle receptor binding activity. Involved in several processes, including positive regulation of cell communication; postsynaptic membrane organization; and regulation of neurotransmitter receptor activity. Acts upstream of or within several processes, including nervous system development; peptidyl-tyrosine phosphorylation; and thyroid hormone metabolic process. Located in several cellular components, including dendrite; extracellular matrix; and extracellular space. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study schizophrenia. Human ortholog(s) of this gene implicated in Norman-Roberts syndrome; autistic disorder; and familial temporal lobe epilepsy 7. Orthologous to human RELN (reelin). [provided by Alliance of Genome Resources, Apr 2022]