Rdx - radixin

Enables protein domain specific binding activity. Involved in cellular response to thyroid hormone stimulus; establishment of protein localization; and positive regulation of G1/S transition of mitotic cell cycle. Acts upstream of or within apical protein localization and microvillus assembly. Located in several cellular components, including lamellipodium; microvillus; and ruffle. Colocalizes with plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and sensory organ. Used to study Dubin-Johnson syndrome. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 24. Orthologous to human RDX (radixin). [provided by Alliance of Genome Resources, Apr 2022]