Human
CELSR3 - Cadherin EGF LAG Seven-pass G-type Receptor 3
Alias:
FMI1
EGFL1
HFMI1
MEGF2
ADGRC3
CDHF11
RESDA1
This gene belongs to the flamingo subfamily, which is included in the cadherin superfamily. The flamingo cadherins consist of nonclassic-type cadherins that do not interact with catenins. They are plasma membrane proteins containing seven epidermal growth factor-like repeats, nine cadherin domains and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic feature of their subfamily. The encoded protein may be involved in the regulation of contact-dependent neurite growth and may play a role in tumor formation. [provided by RefSeq, Jun 2013]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CELSR3 Genetics information (-)
GRCh38
Chr 3: 48636463 - 48662886
Sequence Homology
 Gene Length | ||
| Human | Chr 3 | 26424 bp |
| Mouse | Chr 9 | 26925 bp |
| Rat | Chr 8 | 27764 bp |
 Exon Count | ||
| Human | NM_001407.3 | 35 |
| Mouse | NM_001359572.1 | 35 |
| Rat | NM_031320.1 | 35 |
 Transcript Length | ||
| Human | NM_001407.3 | 11933 bp |
| Mouse | NM_001359572.1 | 11846 bp |
| Rat | NM_031320.1 | 11868 bp |
 homology Sequence Alignment | ||
| Human | NM_001407.3 | 100% |
| Mouse | NM_001359572.1 | 86.5% |
| Rat | NM_031320.1 | 86.3% |
 Protein Length | ||
| Human | NP_001398.2 | 3312 aa |
| Mouse | NP_001346501.1 | 3309 aa |
| Rat | NP_112610.1 | 3313 aa |
 Protein homology Sequence Alignment | ||
| Human | NP_001398.2 | 100% |
| Mouse | NP_001346501.1 | 92.1% |
| Rat | NP_112610.1 | 91.7% |
Related Diseases and Mutations
This section is currently in development, please stay tuned for our data updates.
Transcripts & Proteins
There are 1 transcripts and 1 protein isoforms for CELSR3 gene.
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
There is currently no available transcript or protein sequence found to be associated with the gene.
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
5 Results, 10 per Page
1
Related Drugs
This section is currently in development, please stay tuned for our data updates.
References Literature
Numbers
Title
PMID
Journal
Year
IF
7 Results, 10 per Page
1
