Rasgrf1 - RAS protein-specific guanine nucleotide-releasing factor 1

Enables glutamate receptor binding activity. Involved in activation of GTPase activity; neuron projection development; and regulation of Rac protein signal transduction. Acts upstream of or within cell population proliferation; regulation of NMDA receptor activity; and regulation of neuronal synaptic plasticity. Located in cytosol and growth cone. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; nervous system; and sensory organ. Orthologous to human RASGRF1 (Ras protein specific guanine nucleotide releasing factor 1). [provided by Alliance of Genome Resources, Apr 2022]