Rapsn - receptor-associated protein of the synapse

Enables acetylcholine receptor binding activity. Acts upstream of or within positive regulation of neuron apoptotic process. Located in Golgi apparatus; neuromuscular junction; and plasma membrane. Is active in postsynaptic specialization membrane. Is expressed in several structures, including central nervous system; embryo mesenchyme; forelimb bud; limb; and skeletal musculature. Used to study congenital myasthenic syndrome 11. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 11 and fetal akinesia deformation sequence syndrome 2. Orthologous to human RAPSN (receptor associated protein of the synapse). [provided by Alliance of Genome Resources, Apr 2022]