Rad21 - RAD21 cohesin complex component

Predicted to enable chromatin binding activity. Involved in negative regulation of G2/M transition of mitotic cell cycle and negative regulation of mitotic metaphase/anaphase transition. Located in chromatin; chromosome, centromeric region; and condensed nuclear chromosome. Part of cohesin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 4; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human RAD21 (RAD21 cohesin complex component). [provided by Alliance of Genome Resources, Apr 2022]