Rac1 - Rac family small GTPase 1

Enables GTP binding activity; GTP-dependent protein binding activity; and GTPase activity. Involved in several processes, including engulfment of apoptotic cell; nervous system development; and regulation of cell migration. Acts upstream of or within several processes, including cell morphogenesis involved in differentiation; cochlea morphogenesis; and neuron differentiation. Located in several cellular components, including kinocilium; pericentriolar material; and ruffle membrane. Is extrinsic component of plasma membrane. Is expressed in several structures, including central nervous system; early conceptus; embryo mesoderm; eye; and genitourinary system. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 48; colon adenocarcinoma; and pancreatic adenocarcinoma. Orthologous to human RAC1 (Rac family small GTPase 1). [provided by Alliance of Genome Resources, Apr 2022]