Pex5 - peroxisomal biogenesis factor 5

Predicted to enable several functions, including peroxisome targeting sequence binding activity; protein C-terminus binding activity; and protein sequestering activity. Involved in protein import into peroxisome matrix. Acts upstream of or within several processes, including fatty acid metabolic process; mitochondrial membrane organization; and nervous system development. Predicted to be located in Golgi apparatus; membrane; and peroxisomal matrix. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and peroxisomal membrane. Is expressed in genitourinary system; inner ear; liver; and nervous system. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5). [provided by Alliance of Genome Resources, Apr 2022]