Cavin1 - caveolae associated 1

Enables rRNA primary transcript binding activity. Involved in positive regulation of cell motility; protein secretion; and transcription, DNA-templated. Acts upstream of or within termination of RNA polymerase I transcription. Located in caveola; endoplasmic reticulum; and nucleus. Is expressed in several structures, including genitourinary system and sensory organ. Used to study congenital generalized lipodystrophy type 4 and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital generalized lipodystrophy type 4. Orthologous to human CAVIN1 (caveolae associated protein 1). [provided by Alliance of Genome Resources, Apr 2022]