Ptprn2 - protein tyrosine phosphatase, receptor type, N polypeptide 2
Alias:
Phol
PTP-NP
IA2beta
phogrin
mKIAA0387
4930425H11Rik
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Predicted to enable protein tyrosine phosphatase activity. Involved in insulin secretion involved in cellular response to glucose stimulus and neurotransmitter secretion. Located in secretory granule membrane and synaptic vesicle membrane. Is expressed in several structures, including foregut-midgut junction; midgut endoderm; and nervous system. Used to study type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in prediabetes syndrome and type 1 diabetes mellitus. Orthologous to human PTPRN2 (protein tyrosine phosphatase receptor type N2). [provided by Alliance of Genome Resources, Apr 2022]