Ptpn12 - protein tyrosine phosphatase, non-receptor type 12

Enables phosphoprotein phosphatase activity. Acts upstream of or within protein dephosphorylation. Located in cytosol and podosome. Is expressed in several structures, including central nervous system; embryo mesenchyme; extraembryonic component; gut; and retina. Human ortholog(s) of this gene implicated in colorectal cancer. Orthologous to human PTPN12 (protein tyrosine phosphatase non-receptor type 12). [provided by Alliance of Genome Resources, Apr 2022]