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ENMouse
Edem1 - ER degradation enhancer, mannosidase alpha-like 1
Alias:
EDEM
mKIAA0212
A130059K23Rik
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Enables mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Involved in positive regulation of retrograde protein transport, ER to cytosol and trimming of terminal mannose on C branch. Acts upstream of or within ubiquitin-dependent ERAD pathway. Is integral component of endoplasmic reticulum membrane. Is expressed in embryo and liver. Orthologous to human EDEM1 (ER degradation enhancing alpha-mannosidase like protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Basic Information
NCBI
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Edem1 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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