Ptger2 - prostaglandin E receptor 2 (subtype EP2)

Predicted to enable prostaglandin E receptor activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; cellular response to prostaglandin E stimulus; and response to progesterone. Acts upstream of or within regulation of cell population proliferation and response to lipopolysaccharide. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including central nervous system; gut; hemolymphoid system gland; liver and biliary system; and reproductive system. Human ortholog(s) of this gene implicated in asthma, nasal polyps, and aspirin intolerance. Orthologous to human PTGER2 (prostaglandin E receptor 2). [provided by Alliance of Genome Resources, Apr 2022]