Nlgn1 - neuroligin 1

Enables neurexin family protein binding activity. Involved in several processes, including positive regulation of transport; synapse organization; and synaptic vesicle cycle. Acts upstream of or within several processes, including positive regulation of synapse assembly; regulation of respiratory gaseous exchange by nervous system process; and synapse organization. Located in external side of plasma membrane and synapse. Is integral component of plasma membrane. Part of receptor complex. Is active in glutamatergic synapse. Is expressed in blood vessel and brain. Used to study autism spectrum disorder. Orthologous to human NLGN1 (neuroligin 1). [provided by Alliance of Genome Resources, Apr 2022]