Psme3 - proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)

Predicted to enable several functions, including MDM2/MDM4 family protein binding activity; endopeptidase activator activity; and p53 binding activity. Predicted to be involved in negative regulation of extrinsic apoptotic signaling pathway; regulation of G1/S transition of mitotic cell cycle; and regulation of proteolysis. Predicted to act upstream of or within apoptotic process. Predicted to be located in cytosol. Predicted to be part of proteasome activator complex. Predicted to be active in cytoplasm and nucleoplasm. Is expressed in genitourinary system and ventricular layer. Orthologous to human PSME3 (proteasome activator subunit 3). [provided by Alliance of Genome Resources, Apr 2022]