Prodh - proline dehydrogenase

Predicted to enable FAD binding activity; amino acid binding activity; and proline dehydrogenase activity. Predicted to be involved in positive regulation of cell death and proline catabolic process to glutamate. Predicted to act upstream of or within proline metabolic process. Located in mitochondrion. Is expressed in several structures, including adipose tissue; cardiovascular system; central nervous system; forelimb bud; and male reproductive gland or organ. Human ortholog(s) of this gene implicated in amino acid metabolic disorder; hyperprolinemia type 1; and schizophrenia 4. Orthologous to human PRODH (proline dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]