Enables cAMP-dependent protein kinase regulator activity and protein kinase binding activity. Involved in modulation of chemical synaptic transmission. Acts upstream of or within fatty acid metabolic process and learning. Located in several cellular components, including ciliary base; dendrite; and glutamatergic synapse. Part of cAMP-dependent protein kinase complex. Is expressed in several structures, including central nervous system; liver; primary palate; retina; and testis. Orthologous to human PRKAR2B (protein kinase cAMP-dependent type II regulatory subunit beta). [provided by Alliance of Genome Resources, Apr 2022]