Prkar2a - protein kinase, cAMP dependent regulatory, type II alpha

Predicted to enable several functions, including beta-2 adrenergic receptor binding activity; cAMP binding activity; and enzyme binding activity. Involved in modulation of chemical synaptic transmission. Located in cytoplasm and glutamatergic synapse. Part of cAMP-dependent protein kinase complex. Is expressed in several structures, including 1st branchial arch; alimentary system; brain; eye; and genitourinary system. Human ortholog(s) of this gene implicated in congestive heart failure. Orthologous to human PRKAR2A (protein kinase cAMP-dependent type II regulatory subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]