Prkar1b - protein kinase, cAMP dependent regulatory, type I beta

Predicted to enable cAMP binding activity; cAMP-dependent protein kinase inhibitor activity; and protein kinase A catalytic subunit binding activity. Involved in modulation of chemical synaptic transmission and regulation of synaptic vesicle cycle. Acts upstream of or within learning or memory. Located in hippocampal mossy fiber to CA3 synapse and multivesicular body. Part of cAMP-dependent protein kinase complex. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system ganglion; and sensory organ. Orthologous to human PRKAR1B (protein kinase cAMP-dependent type I regulatory subunit beta). [provided by Alliance of Genome Resources, Apr 2022]