Enables palmitoyl-(protein) hydrolase activity. Acts upstream of or within several processes, including grooming behavior; protein catabolic process; and regulation of phospholipase A2 activity. Located in several cellular components, including dendrite; lysosome; and neuronal cell body. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Used to study neuronal ceroid lipofuscinosis 1 and neuronal ceroid lipofuscinosis 3. Human ortholog(s) of this gene implicated in neuronal ceroid lipofuscinosis 1. Orthologous to human PPT1 (palmitoyl-protein thioesterase 1). [provided by Alliance of Genome Resources, Apr 2022]