Ppp1ca - protein phosphatase 1 catalytic subunit alpha

Enables protein serine/threonine phosphatase activity. Involved in circadian regulation of gene expression and entrainment of circadian clock by photoperiod. Acts upstream of or within several processes, including branching morphogenesis of an epithelial tube; positive regulation of extrinsic apoptotic signaling pathway in absence of ligand; and protein dephosphorylation. Located in cytoplasm and nucleoplasm. Is expressed in several structures, including esophagus; eye; and respiratory system. Orthologous to human PPP1CA (protein phosphatase 1 catalytic subunit alpha). [provided by Alliance of Genome Resources, Apr 2022]