Ppib - peptidylprolyl isomerase B

Predicted to enable RNA polymerase binding activity; cyclosporin A binding activity; and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in several processes, including neutrophil chemotaxis; positive regulation by host of viral genome replication; and protein stabilization. Part of endoplasmic reticulum chaperone complex. Is expressed in several structures, including axial skeleton; cranium; otic capsule; and pancreas tip epithelium. Used to study osteogenesis imperfecta type 9. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 9. Orthologous to human PPIB (peptidylprolyl isomerase B). [provided by Alliance of Genome Resources, Apr 2022]