Pou4f3 - POU domain, class 4, transcription factor 3

Enables DNA-binding transcription factor activity and sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including nervous system development; neuromuscular process controlling balance; and sensory perception of sound. Located in nucleus. Is expressed in several structures, including genitourinary system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 15 and autosomal dominant nonsyndromic deafness 52. Orthologous to human POU4F3 (POU class 4 homeobox 3). [provided by Alliance of Genome Resources, Apr 2022]