Serpinf2 - serine (or cysteine) peptidase inhibitor, clade F, member 2

Predicted to enable protease binding activity; protein homodimerization activity; and serine-type endopeptidase inhibitor activity. Involved in several processes, including collagen fibril organization; maintenance of blood vessel diameter homeostasis by renin-angiotensin; and positive regulation of biosynthetic process. Located in collagen-containing extracellular matrix. Is expressed in several structures, including liver; pancreas epithelium; urinary system; and yolk sac. Used to study alpha-2-plasmin inhibitor deficiency. Human ortholog(s) of this gene implicated in COVID-19 and alpha-2-plasmin inhibitor deficiency. Orthologous to human SERPINF2 (serpin family F member 2). [provided by Alliance of Genome Resources, Apr 2022]