Prkce - protein kinase C, epsilon

Enables several functions, including 14-3-3 protein binding activity; actin monomer binding activity; and calcium-independent protein kinase C activity. Involved in several processes, including TRAM-dependent toll-like receptor 4 signaling pathway; positive regulation of actin filament polymerization; and positive regulation of fibroblast migration. Acts upstream of or within several processes, including cellular response to alcohol; positive regulation of cell communication; and regulation of secretion. Located in several cellular components, including cytosol; mitochondrion; and perinuclear region of cytoplasm. Colocalizes with Golgi apparatus. Is expressed in several structures, including central nervous system; genitourinary system; heart ventricle; neural retina; and salivary gland. Orthologous to human PRKCE (protein kinase C epsilon). [provided by Alliance of Genome Resources, Apr 2022]